Phase I Trials: A Strategy of Ongoing Refinement
نویسندگان
چکیده
منابع مشابه
Phase I clinical trials
Phase I trials are conducted to find a dose to use in subsequent trials. They provide data on the rate of adverse events at different dose levels and provide data for studying the pharmacokinetics and pharmacology of the drug. Dose-finding studies that involve therapies with little or no toxicity often enroll healthy volunteers and usually have a control group. Trials in oncology and other life...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 1990
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/82.6.446